Second near-infrared emissive lanthanide complex for fast renal-clearable in vivo optical bioimaging and tiny tumor detection
Researchers around Jianhua Hao demonstrate targeted in vivo imaging with a new emission probe. The fluorescent molecule has a bright and relatively small band emission around 1330nm and is rapidly excreted by a life organism making it very suitable for clinical NIR-II imaging applications.
The researchers show imaging of kidney function and filling of a mouse bladder as well as detection of small millimeter sized tumors. Furthermore, the researchers can combine their technique with X-ray imaging as the probe is a good X-ray imaging agent as well.