Raman Spectroscopy for Clinical ApplicationsLaser Focus World Article written by Peng Zou

New article in Laser Focus World, written by Peng Zou, about the use of Raman spectroscopy as a clinical tool

August 11, 2020

An article written by Teledyne Princeton Instrument’s Peng Zou has been published in Laser Focus World discussing how Raman spectroscopy can be utilized as a clinical tool due to technology advances.

The article discusses the composition of a generic Raman instrument, while going into detail about the unique requirements for a Raman spectrometer used within a medical setting. These requirements highlight how to maximize collection efficiency, the progress in hardware and software, as well as demonstrating the benefits of Raman spectroscopy for biological cell- and tissue-related research.

The article also details how near infrared excitation lasers are able to overcome common issues, such as tissue autofluorescence, as well as penetrate deeper into the tissue providing high spatial resolution in vivo imaging. Spectrograph requirements are also discussed, in which the advantages for dispersive grating-based spectrographs are outlined.

At Teledyne Princeton Instruments we have a wide range of capabilities for biologically based Raman spectroscopy. The TPIR-785 Raman spectroscopy system is optimized for near infrared Raman spectroscopy, offering low autofluorescence and deeper penetration depth for high resolution in vivo imaging. The IsoPlane family offer high spectral resolution for biologically based Raman spectroscopy. The IsoPlane spectrometer has unparalleled technology, minimizing any artefacts within the image while providing the highest spatial resolution for all tissue- and cell-based diagnostics. The IsoPlane 81 is a fully integrated system with the ability to conduct not only Raman spectroscopy, but also fluorescence and absorption spectroscopy in a simple, compact design.